Understanding the political economy of reforming global health initiatives – insights from global and country levels
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Introduction
Since 2000, the number and role of global health initiatives (GHIs) has been growing, with these platforms playing an increasingly important role in pooling and disbursing funds dedicated to specific global health priorities. While recognising their important contribution, there has also been a growth in concerns about distortions and inefficiencies linked to the GHIs and attempts to improve their alignment with country health systems. There is a growing momentum to adjust GHIs to the current broader range of global health threats, such as non-communicable diseases, humanitarian crises and climate change, and against the backdrop of the recent aid cuts. However, reform attempts are challenged by the political economy of the current structures.
Methods
In this article, we draw on research conducted as part of the Future of Global Health Initiatives process. This included a global and regional level analysis as well as three embedded country case studies in Pakistan, South Africa and Senegal. Data were analysed using a political economy framework which focused on actors, context (especially governance and financing) and framing.
Findings
In relation to actors, the GHIs themselves have become increasingly complex (both internally and in their interrelations with other global health actors and one another). They have a large range of clients (including at national level and amongst multilateral agencies) which function as collaborators as well as competitors. Historically there have been few incentives for any of the actors to maximise collaboration given the competitive funding landscape. Power to exert pressure for reforms sits ultimately with bilateral and private funders, though single-issue northern non-governmental organisations (NGOs) are also cited as important influencers. Funders have not collaborated to enable reforms, despite concerns amongst a number of them, because of the helpful functional role of GHIs, which serves funder interests. Some key global boards are reported to be engineered for stasis, and there are widespread concerns about lack of transparency and over-claiming (by some GHIs) of their results. Framing of narratives about achievements and challenges is important to enable or block reforms and are vigorously contested, with stakeholders often selecting different outcomes to emphasise in justifying positions.
Conclusion
GHIs have played an important role in the global health ecosystem but despite formal accountability structures to include recipient governments, substantive accountability has been focused upwards to funders, with risk management strategies which prioritise tracking resources more than improved national health system performance. Achieving consensus on reforms will be challenging but current funding pressures and new threats are creating a sense of urgency, which may shift positions. Political economy analysis can model and influence these debates.
Citation
Witter, S., Palmer, N., Jouhaud, R. et al. Understanding the political economy of reforming global health initiatives – insights from global and country levels. Global Health 21, 40 (2025). https://doi.org/10.1186/s12992-025-01129-0
Read this Globalization and Health journal article here. [opens new tab]
Further information
- Blog post – Money Talks: The Lusaka Agenda Financing Alignment Indicators. January 2025. Centre for Global Development [Opens new tab]
- Reimagining the future of global health initiatives (2024) – a presentation
- Tracking Delivery on the Lusaka Agenda, Policy Paper, Sophie Witter and Pete Baker, 2024 [opens new tab]
- The Lusaka Agenda Tracker: What Gets Measured Gets Done, blog post, Sophie Witter and Peter Baker, 2024 [opens new tab]
- Witter, S. et al. (2023) Reimagining the Future of Global Health Initiatives. Final Report for Wellcome Trust/Government of Norway [Opens new tab]
- The Lusaka Agenda: Conclusions of the Future of Global Health Initiatives Process. December 2023. FGHI secretariat [Opens new tab]
- A case study on ReBUILD’s contribution to the Future of Global Health Initiatives can be found here.